A tunable coarse-grained model for ligand-receptor interaction.

Cell-surface receptors are the most common target for therapeutic drugs. The design and optimization of next generation synthetic drugs require a detailed understanding of the interaction with their corresponding receptors. Mathematical approximations to study ligand-receptor systems based on reacti...

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Bibliographic Details
Main Authors: Teresa Ruiz-Herrero, Javier Estrada, Raúl Guantes, David G Miguez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3828130?pdf=render