Neurotoxin Merging: A Strategy Deployed by the Venom of the Spider <i>Cupiennius salei</i> to Potentiate Toxicity on Insects

Neurotoxin Merging: A Strategy Deployed by the Venom of the Spider <i>Cupiennius salei</i> to Potentiate Toxicity on Insects

The venom of <i>Cupiennius salei</i> is composed of dozens of neurotoxins, with most of them supposed to act on ion channels. Some insecticidal monomeric neurotoxins contain an α-helical part besides their inhibitor cystine knot (ICK) motif (type 1). Other neurotoxins have, besides the I...

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Bibliographic Details
Main Authors: Benjamin Clémençon, Lucia Kuhn-Nentwig, Nicolas Langenegger, Lukas Kopp, Steve Peigneur, Jan Tytgat, Wolfgang Nentwig, Benjamin P. Lüscher
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Toxins
Subjects:
neurotoxin merging
Cupiennius salei
venom
CsTx-13
microscale thermophoresis
bioassay
Online Access:https://www.mdpi.com/2072-6651/12/4/250

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https://www.mdpi.com/2072-6651/12/4/250

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