Genetic Stabilization by p53 Involves Growth Regulatory and Repair Pathways

p53 performs a plethora of activities, which are directed towards the maintenance of the genomic integrity and constitute its universal role as a tumor suppressor. 1000 to 10000 latent p53 molecules are permanently available in order to monitor DNA exchange processes in mitotically growing cells. Af...

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Bibliographic Details
Main Author: Lisa Wiesmüller
Format: Article
Language:English
Published: Hindawi Limited 2001-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/S1110724301000043