Implanted subcutaneous versus intraperitoneal bioscaffold seeded with hepatocyte-like cells: functional evaluation

Implanted subcutaneous versus intraperitoneal bioscaffold seeded with hepatocyte-like cells: functional evaluation

Abstract Background and objectives The X-linked bleeding disorder, hemophilia A, is caused by defective production of factor VIII (FVIII). Hemophilic patients require regular FVIII infusions. Recombinant factor replacement poses the safest line of therapy. However, its main drawbacks are high expens...

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Bibliographic Details
Main Authors: Amal Elham Fares, Hala Gabr, Asmaa Mohammed ShamsEldeen, Haithem A. M. Farghali, Mazen Mohamed Salem Mohamed Rizk, Bassem Essam Mahmoud, Ahmed Bakr Ahmed Tammam, Ayman Magdy Ahmed Mahmoud, Alaa Abdulfattah Mahmoud Suliman, Mohamed Abdelhamid Ali Ayyad, Sahar Hassan Ahmed, Rokia Mohamad Hassan
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Stem Cell Research & Therapy
Subjects:
Hemophilia A
Bioscaffold
Stem cells
Factor VIII
Online Access:https://doi.org/10.1186/s13287-021-02531-2

Internet

https://doi.org/10.1186/s13287-021-02531-2

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