Exploring new potential role of DDB2 by host cell reactivation assay in human tumorigenic cells

Exploring new potential role of DDB2 by host cell reactivation assay in human tumorigenic cells

Abstract Background The Host Cell Reactivation assay (HCR) allows studying the DNA repair capability in different types of human cells. This assay was carried out to assess the ability in removing UV-lesions from DNA, thus verifying NER efficiency. Previously we have shown that DDB2, a protein invol...

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Bibliographic Details
Main Authors: Elisabetta Bassi, Paola Perucca, Isabella Guardamagna, Ennio Prosperi, Lucia A. Stivala, Ornella Cazzalini
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Cancer
Subjects:
DNA damage response
DNA damaged binding protein 2
Global genome nucleotide excision repair
Xeroderma Pigmentosum group G
RNA polymerase II
Online Access:http://link.springer.com/article/10.1186/s12885-019-6258-0

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http://link.springer.com/article/10.1186/s12885-019-6258-0

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