IL-33/ST2 Axis in Organ Fibrosis

Interleukin 33 (IL-33) is highly expressed in barrier sites, acting via the suppression of tumorigenicity 2 receptor (ST2). IL-33/ST2 axis has long been known to play a pivotal role in immunity and cell homeostasis by promoting wound healing and tissue repair. However, it is also involved in the los...

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Bibliographic Details
Main Authors: Ourania S. Kotsiou, Konstantinos I. Gourgoulianis, Sotirios G. Zarogiannis
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
ST2
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02432/full