In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants

In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants

In animal nutrition, mycotoxins are important feed contaminants. Among them, ochratoxins (OTA) and aflatoxins (AF) have several biological activities, including acute toxicity, teratogenicity, mutagenicity, immunotoxicity and carcinogenicity (Creepy, 2002). Obviously, toxicity of mycotoxins is a ris...

Full description

Bibliographic Details
Main Authors: F. Cheli, B. Bertasi, E. Pavoni, R. Rebucci, N. Losio, L. Sangalli, E. Fusi, A. Baldi
Format: Article
Language:English
Published: Taylor & Francis Group 2011-03-01
Series:Italian Journal of Animal Science
Subjects:
cytotoxicity, mycotoxins, antioxidants, ROS
Online Access:http://www.aspajournal.it/index.php/ijas/article/view/2008
id doaj-8b40233a25b34d3380cf8a903ee5e80c
record_format Article
spelling doaj-8b40233a25b34d3380cf8a903ee5e80c2020-11-25T00:44:19ZengTaylor & Francis GroupItalian Journal of Animal Science1594-40771828-051X2011-03-0121S23123310.4081/ijas.2003.s1.231In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidantsF. CheliB. BertasiE. PavoniR. RebucciN. LosioL. SangalliE. FusiA. BaldiIn animal nutrition, mycotoxins are important feed contaminants. Among them, ochratoxins (OTA) and aflatoxins (AF) have several biological activities, including acute toxicity, teratogenicity, mutagenicity, immunotoxicity and carcinogenicity (Creepy, 2002). Obviously, toxicity of mycotoxins is a risk factor not only for animals but for humans, too (Hussein et al., 2001). Deficiencies of certain nutritional factors e.g. micronutrients may predispose or enhance individuals to the toxic effects of mycotoxins (Atroshi et al., 2002). It is well known that antioxidants like vitamin E, protect cellular membranes from oxidative damage.........http://www.aspajournal.it/index.php/ijas/article/view/2008cytotoxicity, mycotoxins, antioxidants, ROS
collection DOAJ
language English
format Article
sources DOAJ
author F. Cheli
B. Bertasi
E. Pavoni
R. Rebucci
N. Losio
L. Sangalli
E. Fusi
A. Baldi
spellingShingle F. Cheli
B. Bertasi
E. Pavoni
R. Rebucci
N. Losio
L. Sangalli
E. Fusi
A. Baldi
In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants
Italian Journal of Animal Science
cytotoxicity, mycotoxins, antioxidants, ROS
author_facet F. Cheli
B. Bertasi
E. Pavoni
R. Rebucci
N. Losio
L. Sangalli
E. Fusi
A. Baldi
author_sort F. Cheli
title In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants
title_short In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants
title_full In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants
title_fullStr In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants
title_full_unstemmed In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants
title_sort in vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin a and aflatoxin b1: protective role of antioxidants
publisher Taylor & Francis Group
series Italian Journal of Animal Science
issn 1594-4077
1828-051X
publishDate 2011-03-01
description In animal nutrition, mycotoxins are important feed contaminants. Among them, ochratoxins (OTA) and aflatoxins (AF) have several biological activities, including acute toxicity, teratogenicity, mutagenicity, immunotoxicity and carcinogenicity (Creepy, 2002). Obviously, toxicity of mycotoxins is a risk factor not only for animals but for humans, too (Hussein et al., 2001). Deficiencies of certain nutritional factors e.g. micronutrients may predispose or enhance individuals to the toxic effects of mycotoxins (Atroshi et al., 2002). It is well known that antioxidants like vitamin E, protect cellular membranes from oxidative damage.........
topic cytotoxicity, mycotoxins, antioxidants, ROS
url http://www.aspajournal.it/index.php/ijas/article/view/2008
work_keys_str_mv AT fcheli invitroevaluationofcytotoxicityandoxidativedamageinducedbyochratoxinaandaflatoxinb1protectiveroleofantioxidants
AT bbertasi invitroevaluationofcytotoxicityandoxidativedamageinducedbyochratoxinaandaflatoxinb1protectiveroleofantioxidants
AT epavoni invitroevaluationofcytotoxicityandoxidativedamageinducedbyochratoxinaandaflatoxinb1protectiveroleofantioxidants
AT rrebucci invitroevaluationofcytotoxicityandoxidativedamageinducedbyochratoxinaandaflatoxinb1protectiveroleofantioxidants
AT nlosio invitroevaluationofcytotoxicityandoxidativedamageinducedbyochratoxinaandaflatoxinb1protectiveroleofantioxidants
AT lsangalli invitroevaluationofcytotoxicityandoxidativedamageinducedbyochratoxinaandaflatoxinb1protectiveroleofantioxidants
AT efusi invitroevaluationofcytotoxicityandoxidativedamageinducedbyochratoxinaandaflatoxinb1protectiveroleofantioxidants
AT abaldi invitroevaluationofcytotoxicityandoxidativedamageinducedbyochratoxinaandaflatoxinb1protectiveroleofantioxidants
_version_ 1725275013540478976

Similar Items