A network of epigenetic modifiers and DNA repair genes controls tissue-specific copy number alteration preference

Copy number alterations (CNAs) in cancer patients show a large variability in their number, length and position, but the sources of this variability are not known. CNA number and length are linked to patient survival, suggesting clinical relevance. We have identified genes that tend to be mutated in...

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Bibliographic Details
Main Authors: Dina Cramer, Luis Serrano, Martin H Schaefer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/16519