Differential Cell Susceptibilities to KrasG12D in the Setting of Obstructive Chronic PancreatitisSummary

Background & Aims: Activating mutation of the KRAS gene is common in some cancers, such as pancreatic cancer, but rare in other cancers. Chronic pancreatitis is a predisposing condition for pancreatic ductal adenocarcinoma (PDAC), but how it synergizes with KRAS mutation is not known. Methods: W...

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Bibliographic Details
Main Authors: Chanjuan Shi, Fong Cheng Pan, Jessica N. Kim, M. Kay Washington, Chandrasekhar Padmanabhan, Christian T. Meyer, Janel L. Kopp, Maike Sander, Maureen Gannon, R. Daniel Beauchamp, Christopher V. Wright, Anna L. Means
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X19300888