Activation of MAT2A-RIP1 signaling axis reprograms monocytes in gastric cancer

Background The activation of tumor-associated macrophages (TAMs) facilitates the progression of gastric cancer (GC). Cell metabolism reprogramming has been shown to play a vital role in the polarization of TAMs. However, the role of methionine metabolism in function of TAMs remains to be explored.Me...

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Bibliographic Details
Main Authors: Hui Yang, Ping Wan, Ye Hu, YiRen Hu, Mingzhe Ma, Kun Lv
Format: Article
Language:English
Published: BMJ Publishing Group 2021-02-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/2/e001364.full