Combined Effect of Midazolam and Bone Morphogenetic Protein-2 for Differentiation Induction from C2C12 Myoblast Cells to Osteoblasts

Combined Effect of Midazolam and Bone Morphogenetic Protein-2 for Differentiation Induction from C2C12 Myoblast Cells to Osteoblasts

In drug repositioning research, a new concept in drug discovery and new therapeutic opportunities have been identified for existing drugs. Midazolam (MDZ) is an anesthetic inducer used for general anesthesia. Here, we demonstrate the combined effects of bone morphogenetic protein-2 (BMP-2) and MDZ o...

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Bibliographic Details
Main Authors: Yukihiko Hidaka, Risako Chiba-Ohkuma, Takeo Karakida, Kazuo Onuma, Ryuji Yamamoto, Keiko Fujii-Abe, Mari M. Saito, Yasuo Yamakoshi, Hiroshi Kawahara
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pharmaceutics
Subjects:
drug repositioning
cell
hydroxyapatite
bone
midazolam
Online Access:https://www.mdpi.com/1999-4923/12/3/218

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https://www.mdpi.com/1999-4923/12/3/218

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