Synthesis of Some New Fluorinated Hexahydroquinoline and Acridinedione Derivatives in Trifluoroethanol

This article describes one-pot synthesis of new fluorinated hexahydroquinoline derivatives via unsymmetric Hantzsch reaction involving 5-trifluoromethyl-1,3-cyclohexanedione, aldehydes, acetoacetate ester, and ammonium acetate in trifluoroethanol (TFE). The reaction is simple and rapid with high yie...

Full description

Bibliographic Details
Main Authors: Cosmas O. Okoro, Mumiye A. Ogunwale, Tasneem Siddiquee
Format: Article
Language:English
Published: MDPI AG 2012-04-01
Series:Applied Sciences
Subjects:
Online Access:http://www.mdpi.com/2076-3417/2/2/368