The brain-specific RasGEF very-KIND is required for normal dendritic growth in cerebellar granule cells and proper motor coordination.

The brain-specific RasGEF very-KIND is required for normal dendritic growth in cerebellar granule cells and proper motor coordination.

Very-KIND/Kndc1/KIAA1768 (v-KIND) is a brain-specific Ras guanine nucleotide exchange factor carrying two sets of the kinase non-catalytic C-lobe domain (KIND), and is predominantly expressed in cerebellar granule cells. Here, we report the impact of v-KIND deficiency on dendritic and synaptic growt...

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Bibliographic Details
Main Authors: Kanehiro Hayashi, Asako Furuya, Yuriko Sakamaki, Takumi Akagi, Yo Shinoda, Tetsushi Sadakata, Tsutomu Hashikawa, Kazuki Shimizu, Haruka Minami, Yoshitake Sano, Manabu Nakayama, Teiichi Furuichi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5338823?pdf=render

Internet

http://europepmc.org/articles/PMC5338823?pdf=render

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