Sjögren’s Syndrome Minor Salivary Gland CD4<sup>+</sup> Memory T Cells Associate with Glandular Disease Features and have a Germinal Center T Follicular Helper Transcriptional Profile

Sjögren’s Syndrome Minor Salivary Gland CD4<sup>+</sup> Memory T Cells Associate with Glandular Disease Features and have a Germinal Center T Follicular Helper Transcriptional Profile

To assess the types of salivary gland (SG) T cells contributing to Sjögren’s syndrome (SS), we evaluated SG T cell subtypes for association with disease features and compared the SG CD4<sup>+</sup> memory T cell transcriptomes of subjects with either primary SS (pSS) or non-SS sicca (nSS...

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Bibliographic Details
Main Authors: Michelle L. Joachims, Kerry M. Leehan, Mikhail G. Dozmorov, Constantin Georgescu, Zijian Pan, Christina Lawrence, M. Caleb Marlin, Susan Macwana, Astrid Rasmussen, Lida Radfar, David M. Lewis, Donald U. Stone, Kiely Grundahl, R. Hal Scofield, Christopher J. Lessard, Jonathan D. Wren, Linda F. Thompson, Joel M. Guthridge, Kathy L. Sivils, Jacen S. Moore, A. Darise Farris
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Journal of Clinical Medicine
Subjects:
sjögren’s syndrome
salivary gland
T lymphocytes
transcriptome
Online Access:https://www.mdpi.com/2077-0383/9/7/2164

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https://www.mdpi.com/2077-0383/9/7/2164

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