Phenotype of p53 wild-type epitope-specific T cells in the circulation of patients with head and neck cancer

Abstract CD8+ cytotoxic T-cell (CTL) specific for non-mutated, wild type (wt) sequence p53 peptides derived from wt or mutant p53 molecules expressed in head and neck squamous cell carcinomas (HNSCC) have been detected in the circulation of patients with this disease. The frequency and differentiati...

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Bibliographic Details
Main Authors: Andreas E. Albers, Xu Qian, Andreas M. Kaufmann, Daphne Mytilineos, Robert L. Ferris, Thomas K. Hoffmann, Albert B. DeLeo
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-29067-5