The activation of CD14, TLR4, and TLR2 by mmLDL induces IL-1β, IL-6, and IL-10 secretion in human monocytes and macrophages

The activation of CD14, TLR4, and TLR2 by mmLDL induces IL-1β, IL-6, and IL-10 secretion in human monocytes and macrophages

<p>Abstract</p> <p>Atherosclerosis is considered a chronic inflammatory disease in which monocytes and macrophages are critical. These cells express CD14, toll-like receptor (TLR) 2, and TLR4 on their surfaces, are activated by minimally modified low-density lipoprotein (mmLDL) and...

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Bibliographic Details
Main Authors: Blanco-Favela Francisco, Madrid-Miller Alejandra, Tesoro-Cruz Emiliano, Montoya-Díaz Eduardo, Zenteno Edgar, Ledesma-Soto Yadira, Legorreta-Haquet Maria, Chávez-Rueda Karina, Chávez-Sánchez Luis
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Lipids in Health and Disease
Online Access:http://www.lipidworld.com/content/9/1/117

Internet

http://www.lipidworld.com/content/9/1/117

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