Inflammatory Cytokine Tumor Necrosis Factor α Confers Precancerous Phenotype in an Organoid Model of Normal Human Ovarian Surface Epithelial Cells

Inflammatory Cytokine Tumor Necrosis Factor α Confers Precancerous Phenotype in an Organoid Model of Normal Human Ovarian Surface Epithelial Cells

In this study, we established an in vitro organoid model of normal human ovarian surface epithelial (HOSE) cells. The spheroids of these normal HOSE cells resembled epithelial inclusion cysts in human ovarian cortex, which are the cells of origin of ovarian epithelial tumor. Because there are stron...

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Bibliographic Details
Main Authors: Joseph Kwong, Franky Leung Chan, Kwong-kwok Wong, Michael J. Birrer, Kyra M. Archibald, Frances R. Balkwill, Ross S. Berkowitz, Samuel C. Mok
Format: Article
Language:English
Published: Elsevier 2009-06-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558609801103

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http://www.sciencedirect.com/science/article/pii/S1476558609801103

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