Tetrahedral framework nucleic acids as an advanced drug delivery system for oligonucleotide drugs

Nucleic acid therapy has played a promising role in the treatment of many diseases, such as cancer, infections, immune diseases, and neurodegenerative diseases. However, its application is still limited mainly because of poor cell-entry performance and low resistance to in vivo degradation. Tetrahed...

Full description

Bibliographic Details
Main Authors: Yuhao Liu, Zhiqiang Liu, Weitong Cui, Yanjing Li, Xin Qin, Mei Zhang, Yunfeng Lin
Format: Article
Language:English
Published: AIP Publishing LLC 2020-10-01
Series:APL Materials
Online Access:http://dx.doi.org/10.1063/5.0025211