Intracerebroventricular injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer’s disease dementia: a phase I clinical trial

Intracerebroventricular injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer’s disease dementia: a phase I clinical trial

Abstract Backgrounds Alzheimer’s disease is the most common cause of dementia, and currently, there is no disease-modifying treatment. Favorable functional outcomes and reduction of amyloid levels were observed following transplantation of mesenchymal stem cells (MSCs) in animal studies. Objectives...

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Bibliographic Details
Main Authors: Hee Jin Kim, Kyung Rae Cho, Hyemin Jang, Na Kyung Lee, Young Hee Jung, Jun Pyo Kim, Jung Il Lee, Jong Wook Chang, Seongbeom Park, Sung Tae Kim, Seung Whan Moon, Sang Won Seo, Soo Jin Choi, Duk L. Na
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Mesenchymal stem cell
Intracerebroventricular injection
Phase I/IIa
Online Access:https://doi.org/10.1186/s13195-021-00897-2

Internet

https://doi.org/10.1186/s13195-021-00897-2

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