Encapsulation of Alpha-1 antitrypsin in PLGA nanoparticles: In Vitro characterization as an effective aerosol formulation in pulmonary diseases

Encapsulation of Alpha-1 antitrypsin in PLGA nanoparticles: In Vitro characterization as an effective aerosol formulation in pulmonary diseases

<p>Abstract</p> <p>Background</p> <p>Alpha 1- antitrypsin (α1AT) belongs to the superfamily of serpins and inhibits different proteases. α1AT protects the lung from cellular inflammatory enzymes. In the absence of α1AT, the degradation of lung tissue results to pulmonar...

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Bibliographic Details
Main Authors: Pirooznia Nazanin, Hasannia Sadegh, Lotfi Abbas, Ghanei Mostafa
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Journal of Nanobiotechnology
Subjects:
Cytotoxicity
DSC (differential scanning calorimetry)
FTIR
Nanoparticle
Sustained drug release
XRD (x-ray diffraction)
Online Access:http://www.jnanobiotechnology.com/content/10/1/20

Internet

http://www.jnanobiotechnology.com/content/10/1/20

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