Interactions between Cancer-Associated Fibroblasts and T Cells in the Pancreatic Tumor Microenvironment and the Role of Chemokines

Less than 10% of patients diagnosed with pancreatic ductal adenocarcinoma (PDAC) survive 5 years or more, making it one of the most fatal cancers. Accumulation of T cells in pancreatic tumors is associated with better prognosis, but immunotherapies to enhance the anti-tumor activity of infiltrating...

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Bibliographic Details
Main Authors: Laia Gorchs, Helen Kaipe
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/12/2995