Vaccinia Virus LC16m8∆ as a Vaccine Vector for Clinical Applications
The LC16m8 strain of vaccinia virus, the active ingredient in the Japanese smallpox vaccine, was derived from the Lister/Elstree strain. LC16m8 is replication-competent and has been administered to over 100,000 infants and 3,000 adults with no serious adverse reactions. Despite this outstanding safe...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-10-01
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Series: | Vaccines |
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Online Access: | http://www.mdpi.com/2076-393X/2/4/755 |