Vaccinia Virus LC16m8∆ as a Vaccine Vector for Clinical Applications

The LC16m8 strain of vaccinia virus, the active ingredient in the Japanese smallpox vaccine, was derived from the Lister/Elstree strain. LC16m8 is replication-competent and has been administered to over 100,000 infants and 3,000 adults with no serious adverse reactions. Despite this outstanding safe...

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Bibliographic Details
Main Authors: Minoru Kidokoro, Hisatoshi Shida
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Vaccines
Subjects:
B5R
MVA
DIs
SIV
HIV
Online Access:http://www.mdpi.com/2076-393X/2/4/755