Geometry Dynamics of α-Helices in Different Class I Major Histocompatibility Complexes

MHC α-helices form the antigen-binding cleft and are of particular interest for immunological reactions. To monitor these helices in molecular dynamics simulations, we applied a parsimonious fragment-fitting method to trace the axes of the α-helices. Each resulting axis was fitted by polynomials in...

Full description

Bibliographic Details
Main Authors: Reiner Ribarics, Michael Kenn, Rudolf Karch, Nevena Ilieva, Wolfgang Schreiner
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2015/173593