Phenylalanine-rich peptides potently bind ESAT6, a virulence determinant of Mycobacterium tuberculosis, and concurrently affect the pathogen's growth.

Phenylalanine-rich peptides potently bind ESAT6, a virulence determinant of Mycobacterium tuberculosis, and concurrently affect the pathogen's growth.

BACKGROUND:The secretory proteins of Mycobacterium tuberculosis (M. tuberculosis) have been known to be involved in the virulence, pathogenesis as well as proliferation of the pathogen. Among this set, many proteins have been hypothesized to play a critical role at the genesis of the onset of infect...

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Bibliographic Details
Main Authors: Krishan Kumar, Megha Tharad, Swetha Ganapathy, Geeta Ram, Azeet Narayan, Jameel Ahmad Khan, Rana Pratap, Anamika Ghosh, Sachin Kumar Samuchiwal, Sushil Kumar, Kuhulika Bhalla, Deepti Gupta, Krishnamurthy Natarajan, Yogendra Singh, Anand Ranganathan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2768790?pdf=render

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