A three-hybrid system to probe in vivo protein-protein interactions: application to the essential proteins of the RD1 complex of M. tuberculosis.

by Megha Tharad, Sachin Kumar Samuchiwal, Kuhulika Bhalla, Anamika Ghosh, Krishan Kumar, Sushil Kumar, Anand Ranganathan
Published 2011-01-01

Expression of the ARPC4 subunit of human Arp2/3 severely affects mycobacterium tuberculosis growth and suppresses immunogenic response in murine macrophages.

by Anamika Ghosh, Sultan Tousif, Debapriya Bhattacharya, Sachin K Samuchiwal, Kuhulika Bhalla, Megha Tharad, Sushil Kumar, Prem Prakash, Purnima Kumar, Gobardhan Das, Anand Ranganathan
Published 2013-01-01

A novel peptide interferes with Mycobacterium tuberculosis virulence and survival

by Sachin Kumar Samuchiwal, Sultan Tousif, Dhiraj Kumar Singh, Arun Kumar, Anamika Ghosh, Kuhulika Bhalla, Prem Prakash, Sushil Kumar, Ashish Chandra Trivedi, Maitree Bhattacharyya, Gobardhan Das, Anand Ranganathan
Published 2014-01-01

Phenylalanine-rich peptides potently bind ESAT6, a virulence determinant of Mycobacterium tuberculosis, and concurrently affect the pathogen's growth.

by Krishan Kumar, Megha Tharad, Swetha Ganapathy, Geeta Ram, Azeet Narayan, Jameel Ahmad Khan, Rana Pratap, Anamika Ghosh, Sachin Kumar Samuchiwal, Sushil Kumar, Kuhulika Bhalla, Deepti Gupta, Krishnamurthy Natarajan, Yogendra Singh, Anand Ranganathan
Published 2009-11-01