Genetic variation at selected SNPs in the leptin gene and association of alleles with markers of kidney disease in a Xhosa population of South Africa.

<h4>Background</h4>Chronic kidney disease (CKD) is a significant public health problem that leads to end-stage renal disease (ESRD) with as many as 2 million people predicted to need therapy worldwide by 2010. Obesity is a risk factor for CKD and leptin, the obesity hormone, correlates w...

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Bibliographic Details
Main Authors: Ikechi G Okpechi, Brian L Rayner, Lize van der Merwe, Bongani M Mayosi, Adebowale Adeyemo, Nicki Tiffin, Rajkumar Ramesar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20140086/pdf/?tool=EBI