A simple model system enabling human CD34(+) cells to undertake differentiation towards T cells.

BACKGROUND: Channelling the development of haematopoietic progenitor cells into T lymphocytes is dependent upon a series of extrinsic prompts whose temporal and spatial sequence is critical for a productive outcome. Simple models of human progenitor cells development depend in the main on the use of...

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Bibliographic Details
Main Authors: Antonio Lapenna, Christopher B-Lynch, Chrysa Kapeni, Richard Aspinall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3720953?pdf=render