Mechanisms and Applications of the Anti-cancer Effect of Pharmacological Ascorbic Acid in Cervical Cancer Cells

In recent years, L-ascorbic acid (L-AA), or vitamin C, has been attracting attention as a potential anticancer drug that mediates hydrogen peroxide-induced oxidation and ten-eleven translocation 2-catalyzed DNA demethylation. However, the precise mechanism by which L-AA acts remains unclear. We exam...

Full description

Bibliographic Details
Main Authors: Tsai-Ming Wu, Shu-Ting Liu, Ssu-Yu Chen, Gunng-Shinng Chen, Chia-Chun Wu, Shih-Ming Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
p53
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01483/full