Dehydrocorydaline Protects Against Sepsis-Induced Myocardial Injury Through Modulating the TRAF6/NF-κB Pathway

Dehydrocorydaline Protects Against Sepsis-Induced Myocardial Injury Through Modulating the TRAF6/NF-κB Pathway

We aim to investigate the effect and mechanism of dehydrocorydaline (Deh), an alkaloidal component isolated from Rhizoma corydalis, in the treatment of sepsis-mediated myocardial injury. Lipopolysaccharide (LPS) was taken to construct an in-vitro sepsis-myocardial injury models H9C2 cardiomyocytes....

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Bibliographic Details
Main Authors: Yadong Li, Li Zhang, Ping Zhang, Zhiying Hao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
sepsis
myocardial injury
dehydrocorydaline
TRAF6/NF-κB pathway
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.709604/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.709604/full

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