Transposon Insertion Site Sequencing of Providencia stuartii: Essential Genes, Fitness Factors for Catheter-Associated Urinary Tract Infection, and the Impact of Polymicrobial Infection on Fitness Requirements

Transposon Insertion Site Sequencing of Providencia stuartii: Essential Genes, Fitness Factors for Catheter-Associated Urinary Tract Infection, and the Impact of Polymicrobial Infection on Fitness Requirements

Providencia stuartii is a common cause of polymicrobial catheter-associated urinary tract infections (CAUTIs), particularly during long-term catheterization. However, little is known regarding the pathogenesis of this organism. Using transposon insertion site sequencing (Tn-Seq), we performed a glob...

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Bibliographic Details
Main Authors: Alexandra O. Johnson, Valerie Forsyth, Sara N. Smith, Brian S. Learman, Aimee L. Brauer, Ashley N. White, Lili Zhao, Weisheng Wu, Harry L. T. Mobley, Chelsie E. Armbruster
Format: Article
Language:English
Published: American Society for Microbiology 2020-05-01
Series:mSphere
Subjects:
proteus mirabilis
providencia stuartii
tn-seq
catheter
essential genes
pathogenesis
polymicrobial
transposon
urinary tract infection
Online Access:https://doi.org/10.1128/mSphere.00412-20

Internet

https://doi.org/10.1128/mSphere.00412-20

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