In vitro and in silico Approaches to Study Cytochrome P450-Mediated Interactions
In vitro and in silico models of drug metabolism are utilized regularly in the drug research and development as tools for assessing pharmacokinetic variability and drug-drug interaction risk. The use of in vitro and in silico predictive approaches offers advantages including guiding rational design...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Canadian Society for Pharmaceutical Sciences
2018-01-01
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Series: | Journal of Pharmacy & Pharmaceutical Sciences |
Online Access: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/29323 |