Expression of apolipoprotein C-III in McA-RH7777 cells enhances VLDL assembly and secretion under lipid-rich conditions[S]

Expression of apolipoprotein C-III in McA-RH7777 cells enhances VLDL assembly and secretion under lipid-rich conditions[S]

Apolipoprotein (apo) C-III plays a regulatory role in VLDL lipolysis and clearance. In this study, we determined a potential intracellular role of apoC-III in hepatic VLDL assembly and secretion. Stable expression of recombinant apoC-III in McA-RH7777 cells resulted in increased secretion efficiency...

Full description

Bibliographic Details
Main Authors: Meenakshi Sundaram, Shumei Zhong, Maroun Bou Khalil, Philip H. Links, Yang Zhao, Jahangir Iqbal, M. Mahmood Hussain, Robin J. Parks, Yuwei Wang, Zemin Yao
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Journal of Lipid Research
Subjects:
triacylglycerol
hypotriglyceridemia
hypertriglyceridemia
microsomal triglyceride transfer protein
hepatocyte
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520313857

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520313857

Similar Items