Fatty acid binding proteins stabilize leukotriene A4

Leukotriene A4 (LTA4) is a chemically reactive conjugated triene epoxide product derived from 5-lipoxygenase oxygenation of arachidonic acid. At physiological pH, this reactive compound has a half-life of less than 3 s at 37°C and ∼40 s at 4°C. Regardless of this aqueous instability, LTA4 is an inte...

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Bibliographic Details
Main Authors: Jennifer S. Dickinson Zimmer, Douglas F. Dyckes, David A. Bernlohr, Robert C. Murphy
Format: Article
Language:English
Published: Elsevier 2004-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520341456