In vitro characterization of odorranalectin for peptide-based drug delivery across the blood–brain barrier

Abstract Background The use of siRNA-based gene silencing has been recently underscored as a potential therapeutic strategy for the treatment of neurological disorders. However, the stability of siRNA and other small molecule therapeutics is challenged by their intrinsic instability and limited pass...

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Bibliographic Details
Main Authors: Ravi K. Sajja, Predrag Cudic, Luca Cucullo
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Neuroscience
Subjects:
BBB
Online Access:http://link.springer.com/article/10.1186/s12868-019-0504-x