50% versus 70%: is there a difference between these BCL2 cut-offs in immunohistochemistry for diffuse large B-cell lymphomas (DLBCL)?

50% versus 70%: is there a difference between these BCL2 cut-offs in immunohistochemistry for diffuse large B-cell lymphomas (DLBCL)?

Abstract Introduction The World Health Organization’s (WHO) update of 2017 defines the cut-off for BCL2 in immunohistochemistry (IHC) in 50% of stained cells in diffuse large B-cell lymphomas (DLBCL). The WHO’s 2017 classification, however, has no standardized value. This study analyzes associations...

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Bibliographic Details
Main Authors: Cristiano Claudino Oliveira, Maria Aparecida Custódio Domingues, Isabela Werneck da Cunha, Fernando Augusto Soares
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Surgical and Experimental Pathology
Subjects:
Lymphoma
Non-Hodgkin lymphoma
Immunohistochemistry
In situ hybridization, fluorescence
Genes, BCL2
Genes, MYC
Online Access:http://link.springer.com/article/10.1186/s42047-020-00070-3

Internet

http://link.springer.com/article/10.1186/s42047-020-00070-3

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