Neuroprotective and acetylcholinesterase inhibitory activity of plumbagin in ICV-LPS induced behavioral deficits in rats

Neuroprotective and acetylcholinesterase inhibitory activity of plumbagin in ICV-LPS induced behavioral deficits in rats

Plumbagin (5‑hydroxy-2-methyl-1,4-naphthoquinone), a phytoconstituent has been shown to exhibit potent antioxidant and anti-inflammatory effects. In the present investigation, we explored the neuroprotective effects of plumbagin against intracerebroventricular (ICV) lipopolysaccharide (LPS)-induced...

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Bibliographic Details
Main Authors: Ashok Jangra, Vaishali Chadha, Dinesh Kumar, Vipin Kumar, Mandeep K Arora
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Current Research in Behavioral Sciences
Subjects:
Acetylcholinesterase
Lipopolysaccharide
Plumbagin
Hippocampus
Oxidative-nitrosative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2666518221000474

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http://www.sciencedirect.com/science/article/pii/S2666518221000474

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