Correlation of STAT1 with apoptosis and cell-cycle markers in esophageal squamous cell carcinoma.

We recently found evidence that STAT1 in esophageal squamous carcinoma (ESCC) cells exerts tumor suppressor function, and it regulates five key regulators of apoptosis or cell-cycle progression, including Bcl-2, Bcl-xL, survivin, cyclin D1 and p21. In this study, we confirmed these findings in four...

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Bibliographic Details
Main Authors: Ying Zhang, Yaozhong Zhang, Hailong Yun, Raymond Lai, Min Su
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4250046?pdf=render