Genomic analysis of a Mycobacterium bovis bacillus [corrected] Calmette-Guérin strain isolated from an adult patient with pulmonary tuberculosis..

For years, bacillus Calmette-Guérin (BCG) has served as the unique vaccine against tuberculosis and has generally been regarded as safe. However, a clinical strain labeled 3281 that was isolated from a TB patient was identified to be BCG. Via the combination of next-generation sequencing (NGS) and c...

Full description

Bibliographic Details
Main Authors: Xuming Li, Liping Chen, Yongqiang Zhu, Xia Yu, Jun Cao, Rui Wang, Xinyan Lv, Jin He, Aizhen Guo, Hairong Huang, Huajun Zheng, Siguo Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395146?pdf=render