NFAT5 expression in bone marrow-derived cells enhances atherosclerosis and drives macrophage migration

Objective: We have previously shown that the transcription factor, nuclear factor of activated T-cells 5 (NFAT5), regulates vascular smooth muscle cell phenotypic modulation, but the role of NFAT5 in atherosclerosis is unknown. Our main objective was to determine if NFAT5 expression in bone marrow (...

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Bibliographic Details
Main Authors: Julia A Halterman, H Moo Kwon, Norbert eLeitinger, Brian R Wamhoff
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00313/full