Optimization of an Anti-NMDA Receptor Autoantibody Diagnostic Bioassay

Optimization of an Anti-NMDA Receptor Autoantibody Diagnostic Bioassay

Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is one of the most frequently encountered autoimmune encephalitis. The pathogenesis of both anti-NMDAR encephalitis and schizophrenia involve down-regulation of NMDA receptors. Whether autoantibody-mediated destruction of neuronal NMDA rec...

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Bibliographic Details
Main Authors: Nan-Chang Chiu, Yi-Jie Lin, Ruu-Fen Tzang, Ying-Syuan Li, Hui-Ju Lin, Subir Das, Caleb G. Chen, Chiao-Chicy Chen, Kate Hsu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Neurology
Subjects:
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis
autoantibody (autoAb)
autoimmune encephalitis
schizophrenia
diagnostic test
fluorescein isothiocyanate (FITC)
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00661/full

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https://www.frontiersin.org/article/10.3389/fneur.2018.00661/full

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