Co-occurrence of Rapid Gene Gain and Loss in an Interhospital Outbreak of Carbapenem-Resistant Hypervirulent ST11-K64 Klebsiella pneumoniae

Co-occurrence of Rapid Gene Gain and Loss in an Interhospital Outbreak of Carbapenem-Resistant Hypervirulent ST11-K64 Klebsiella pneumoniae

We report an outbreak of carbapenemase-producing hypervirulent Klebsiella pneumoniae in two hospitals that undergo frequent patient transfers. Analysis of 11 completely assembled genomes showed that the bacteria were ST11-K64 strains. Moreover, 12 single nucleotide polymorphisms (SNPs) identified th...

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Bibliographic Details
Main Authors: XiaoTuan Zhang, JingLin Ouyang, WenWen He, Tong Zeng, Bin Liu, Hongtao Jiang, Yunsheng Zhang, Linlin Zhou, Haijian Zhou, Zhuoran Liu, Logen Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Microbiology
Subjects:
Klebsiella pneumoniae
antibiotic resistance
virulence factors
microevolution
mobile genetic elements
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.579618/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2020.579618/full

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