Dose-Dependent Effect of Flouxetine on 6-OHDA-Induced Catalepsy in Male Rats: A Possible Involvement of 5-HT1A Receptors
Purpose: Progressive loss of dopaminergic neurons of the substantia nigra pars compacta (SNc) in Parkinson’s disease (PD) leads to impairment of motor skills. Several evidences show that the role of serotonergic system in regulation of normal movement is pivotal and mediates via 5-HT1A receptors. Ou...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2013-02-01
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Series: | Advanced Pharmaceutical Bulletin |
Subjects: | |
Online Access: | http://journals.tbzmed.ac.ir/PDF/APB/Manuscript/APB-3-203.pdf |