Development of Postoperative Pain in Patients with End-Stage Knee Osteoarthritis Is Associated with Upregulation of Genes Related to Extracellular Matrix Degradation, Inflammation, and Apoptosis Measured in the Peripheral Blood before Knee Surgery

Development of Postoperative Pain in Patients with End-Stage Knee Osteoarthritis Is Associated with Upregulation of Genes Related to Extracellular Matrix Degradation, Inflammation, and Apoptosis Measured in the Peripheral Blood before Knee Surgery

Osteoarthritis (OA) pain implies an indication for joint replacement in patients with end-stage OA. However, chronic postoperative pain is observed in 10–40% of patients with OA. Here, we identified genes whose expression in the peripheral blood before surgery could denote the risk of postoperative...

Full description

Bibliographic Details
Main Authors: Elena V. Tchetina, Kseniya E. Glemba, Galina A. Markova, Evgeniy A. Naryshkin, Elena A. Taskina, Maksim A. Makarov, Aleksandr M. Lila
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Life
Subjects:
knee osteoarthritis
postoperative pain prediction
gene expression
peripheral blood
Online Access:https://www.mdpi.com/2075-1729/10/10/224

Internet

https://www.mdpi.com/2075-1729/10/10/224

Similar Items