Production of dengue virus-like particles serotype-3 in silkworm larvae and their ability to elicit a humoral immune response in mice

Production of dengue virus-like particles serotype-3 in silkworm larvae and their ability to elicit a humoral immune response in mice

Abstract To develop monovalent dengue virus-like particle for serotype 3 (DENV-LP/3), we prepared and expressed two structural polyprotein constructs using silkworm and Bm5 cells: DENV-3 Capsid-premembrane-envelope (DENV-3CprME) and premembrane-envelope (DENV-3prME). The expressed PA-tagged 3CprME a...

Full description

Bibliographic Details
Main Authors: Doddy Irawan Setyo Utomo, Sabar Pambudi, Fithriyah Sjatha, Tatsuya Kato, Enoch Y. Park
Format: Article
Language:English
Published: SpringerOpen 2020-08-01
Series:AMB Express
Subjects:
Dengue virus
Capsid
Premembrane
Envelope
Dengue virus-like particle
Silkworm
Online Access:http://link.springer.com/article/10.1186/s13568-020-01087-3

Internet

http://link.springer.com/article/10.1186/s13568-020-01087-3

Similar Items