Gluconeogenesis using glycerol as a substrate in bloodstream-form Trypanosoma brucei.

Bloodstream form African trypanosomes are thought to rely exclusively upon glycolysis, using glucose as a substrate, for ATP production. Indeed, the pathway has long been considered a potential therapeutic target to tackle the devastating and neglected tropical diseases caused by these parasites. Ho...

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Bibliographic Details
Main Authors: Julie Kovářová, Rupa Nagar, Joana Faria, Michael A J Ferguson, Michael P Barrett, David Horn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007475