An Efficient Synthesis of Enantiopure (R)-heteroarylpyrimidine Analogs

An Efficient Synthesis of Enantiopure (R)-heteroarylpyrimidine Analogs

An efficient synthesis of enantiopure (R)-heteroarylpyrimidine analogs is described here, which involves introduction of a chiral group, formation and separation of diasteroisomers and final transformation of an amide to an ester. The absolute configuration of the enantiopure HAPs is confirmed by X-...

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Bibliographic Details
Main Authors: Guo-Ming Zhao, Zhi-Bing Zheng, Dong-Mei Zhao, Xiao-Kui Wang, Guang-Qiang Xia, Xiu-Yan Yang, Song Li
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:Molecules
Subjects:
anti-HBV
enantiopure
(R)-heteroarylpyrimidines
chiral separation
diastereomer
Online Access:http://www.mdpi.com/1420-3049/18/9/11144

Internet

http://www.mdpi.com/1420-3049/18/9/11144

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