Brap2 regulates temporal control of NF-κB localization mediated by inflammatory response.

Nuclear factor-kappaB (NF-κB) is critical for the expression of multiple genes involved in inflammatory responses and cellular survival. NF-κB is normally sequestered in the cytoplasm through interaction with an inhibitor of NF-κB (IκB), but inflammatory stimulation induces proteasomal degradation o...

Full description

Bibliographic Details
Main Authors: Osamu Takashima, Fuminori Tsuruta, Yu Kigoshi, Shingo Nakamura, Jaehyun Kim, Megumi C Katoh, Tomomi Fukuda, Kenji Irie, Tomoki Chiba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3598860?pdf=render