Increased expression of Gp96 by HBx-induced NF-κB activation feedback enhances hepatitis B virus production.

Elevated expression of heat shock protein gp96 in hepatitis B virus (HBV)-infected patients is positively correlated with the progress of HBV-induced diseases, but little is known regarding the molecular mechanism of virus-induced gp96 expression and its impact on HBV infection. In this study, up-re...

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Bibliographic Details
Main Authors: Hongxia Fan, Xiaoli Yan, Yu Zhang, Xiaojun Zhang, Yanzhou Gao, Yaxing Xu, Fusheng Wang, Songdong Meng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3679196?pdf=render