IgE alone promotes human lung mast cell survival through the autocrine production of IL-6

<p>Abstract</p> <p>Background</p> <p>Mast cells play a key role in asthma and recent evidence indicates that their ongoing activation in this disease is mediated, in part, <it>via </it>IgE in the absence of antigen. In this study we have examined whether IgE...

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Bibliographic Details
Main Authors: Cockerill Sarah, Cruse Glenn, Bradding Peter
Format: Article
Language:English
Published: BMC 2008-01-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/9/2