Expression of PD-1 and PD-L1 in Extramammary Paget Disease: Implications for Immune-Targeted Therapy

Expression of PD-1 and PD-L1 in Extramammary Paget Disease: Implications for Immune-Targeted Therapy

Extramammary Paget disease (EMPD) is a locally aggressive cutaneous malignancy that usually arises in anogenital or axillary skin. Immune checkpoint inhibitors targeting programmed cell death receptor (PD-1) and/or its ligand (PD-L1) are approved for the treatment of several types of cancer, and res...

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Bibliographic Details
Main Authors: Shakuntala H. Mauzo, Michael T. Tetzlaff, Denái R. Milton, Alan E. Siroy, Priyadharsini Nagarajan, Carlos A. Torres-Cabala, Doina Ivan, Jonathan L. Curry, Courtney W. Hudgens, Jennifer A. Wargo, Aysegul A. Sahin, Curtis A. Pettaway, Victor G. Prieto, Phyu P. Aung
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cancers
Subjects:
extramammary Paget disease
mammary Paget disease
PD-1
PD-L1
immune infiltrate
Online Access:https://www.mdpi.com/2072-6694/11/6/754

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https://www.mdpi.com/2072-6694/11/6/754

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